Biolegend, 369820, Alexa Fluor® 647 anti-human CD326 (EpCAM) Antibody
100tests
Catalog Number: 369820
Send an RFQ.
Category
Loading…
| Verified Reactivity | Human |
|---|---|
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
| Excitation Laser |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:
Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.
| Red Laser (633 nm) |
| Application References(PubMed link indicates BioLegend citation) | Strnad J, et al. 1989. Cancer Res. 49:314. Munz M, et al. 2004. Oncogene 23:5748. Rao CG, et al. 2005. Int. J. Oncol. 27:49. |
|---|
| Product Citations | Carraro G, et al. 2021. Nat Med. 27:806. PubMed Carraro G, et al. 2020. Am J Respir Crit Care Med. 202:1540. PubMed |
|---|
| RRID | AB_2650915 (BioLegend Cat. No. 369819) AB_2650916 (BioLegend Cat. No. 369820) |
|---|
| Structure | Type I transmembrane protein, contains six disulfide bridges, one THYRO domain, approximate molecular weight 40 kD. |
|---|
| Distribution | Highly expressed in bone marrow, colon, lung, and most normal epithelial cells. Also highly expressed on carcinomas of gastrointestinal origin. Expressed during early erythrogenesis. |
|---|
| Function | Homotypic calcium-independent cell adhesion. CD326 is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. |
|---|
| Cell Type | Epithelial cells |
|---|
| Biology Area | Cancer Biomarkers, Cell Biology, Cell Proliferation and Viability, Immunology |
|---|
| Molecular Family | Adhesion Molecules, CD Molecules |
|---|
| Antigen References | 1. Strnad J, et al. 1989. Cancer Res. 49:314. 2. Munz M, et al. 2004. Oncogene 23:5748. 3. Rao CG, et al. 2005. Int. J. Oncol. 27:49. |
|---|
| Gene ID | 4072 |
|---|
| UniProt | View information about CD326 on UniProt.org |
|---|
| Clone | CO17-1A |
|---|
| Regulatory Status | RUO |
|---|
| Other Names | Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, TROP1 |
|---|
| Isotype | Mouse IgG2a, κ |
|---|
