Biolegend, 394509, Alexa Fluor® 488 anti-human CD285 (TLR5) Antibody
25tests
Catalog Number: 394509
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| Verified Reactivity | Human |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Human TLR5 transfectants |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
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| Excitation Laser | Blue Laser (488 nm) |
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| RRID | AB_2892462 (BioLegend Cat. No. 394509) AB_2892462 (BioLegend Cat. No. 394510) |
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| Structure | Type 1 transmembrane protein, 98 kD |
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| Distribution | Neutrophils, classical monocytes, dendritic cells, mucosal epithelium |
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| Function | Interacts with MyD88 and TRAF6 leading to NF-κB activation and production of cytokines. |
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| Ligand/Receptor | flagellin |
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| Cell Type | Dendritic cells, Epithelial cells, Monocytes, Neutrophils |
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| Biology Area | Immunology |
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| Molecular Family | CD Molecules, Toll Like Receptors |
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| Antigen References | Hayashi F, et al. 2001. Nature. 410:1099 Gewirtz AT, et al. 2001. J Immunol. 167:1882 Smith KD, et al. 2002. Curr Top Microbiol Immunol. 270:93 Bambou JC, et al. 2004. J Biol Chem. 279:42984 Sebastiani G, et al. 2000. Genomics. 64:230 Muzio M, et al. 2000. Biochem Soc Trans. 28:563 |
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| Gene ID | 7100 |
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| UniProt | View information about CD285 on UniProt.org |
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| Clone | S16021I |
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| Regulatory Status | RUO |
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| Other Names | SLE1, TIL3, SLEB1, MELIOS, CD285 |
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| Isotype | Mouse IgG2a, κ |
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