Biolegend, 394510, Alexa Fluor® 488 anti-human CD285 (TLR5) Antibody
100tests
Catalog Number: 394510
Send an RFQ.
Category
Loading…
| Verified Reactivity | Human |
|---|---|
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Human TLR5 transfectants |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | FC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:
Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.
| Excitation Laser | Blue Laser (488 nm) |
|---|
| RRID | AB_2892462 (BioLegend Cat. No. 394509) AB_2892462 (BioLegend Cat. No. 394510) |
|---|
| Structure | Type 1 transmembrane protein, 98 kD |
|---|
| Distribution | Neutrophils, classical monocytes, dendritic cells, mucosal epithelium |
|---|
| Function | Interacts with MyD88 and TRAF6 leading to NF-κB activation and production of cytokines. |
|---|
| Ligand/Receptor | flagellin |
|---|
| Cell Type | Dendritic cells, Epithelial cells, Monocytes, Neutrophils |
|---|
| Biology Area | Immunology |
|---|
| Molecular Family | CD Molecules, Toll Like Receptors |
|---|
| Antigen References | Hayashi F, et al. 2001. Nature. 410:1099 Gewirtz AT, et al. 2001. J Immunol. 167:1882 Smith KD, et al. 2002. Curr Top Microbiol Immunol. 270:93 Bambou JC, et al. 2004. J Biol Chem. 279:42984 Sebastiani G, et al. 2000. Genomics. 64:230 Muzio M, et al. 2000. Biochem Soc Trans. 28:563 |
|---|
| Gene ID | 7100 |
|---|
| UniProt | View information about CD285 on UniProt.org |
|---|
| Clone | S16021I |
|---|
| Regulatory Status | RUO |
|---|
| Other Names | SLE1, TIL3, SLEB1, MELIOS, CD285 |
|---|
| Isotype | Mouse IgG2a, κ |
|---|
