Biolegend, 422612, Cell-Vive™ GMP NKp46/CD2 Human NK Cell Activation Beads

Cell-Vive™ GMP NKp46/CD2 Human NK Cell Activation Beads allow for convenient in vitro or ex vivo activation of human NK cells without the need for antigen-presenting cells or feeder cells. Human NK cells are stimulated with anti-NKp46 and anti-CD2 antibodies coated on superparamagnetic microbeads. Simply add the beads directly to isolated NK cells or to PBMCs at a 1:2 bead-to-cell ratio for robust NK cell activation. Excess antibody-coated beads can be removed from the cell suspension using a magnetic separator (some residual beads may be retained in the cell suspension). Some of the downstream applications include functional assays, gene expression analysis, and phenotypic characterization. BioLegend Cell-Vive™ GMP Activation and Expansion Tools are manufactured and tested in accordance with USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue Engineered Products and Ph. Eur. Chapter 5.2.12 in a dedicated GMP facility compliant with ISO 13485:2016. Specifications and processes include