Biolegend, 424203, Flash Phalloidin™ Red 594

Molecular Mass 1535.79 g/mol.  Flash Phalloidin™ Red 594 excites maximally at 590 nm and emits maximally at 611 nm. Phalloidin is a bicyclic peptide that can be found naturally in the death cap mushroom.  This molecule is considered to bind so tightly to F-actin that when ingested by an organism, it will prevent the depolymerization of the actin polymeric filaments which leads to cellular toxicity.  In cell imaging, this is a very useful probe for imaging and stabilizing filamentous F-actin in fixed and permeabilized cells, providing structural and volumetric context to the cell.  Phallotoxins are conjugated to a wide array of fluorophores to enable their use in multicolor microscopy.