Biolegend, 427505, 2-Deoxy-D-glucose
VO27
Catalog Number: 427505
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| Formulation | Lyophilized |
|---|---|
| Preparation | Resuspend 1 g of lyophilized 2-Deoxy-D-Glucose in 60.9 mL of water or PBS to make a 100 mM stock solution. For 250 mg size, add 15.2 mL water or PBS to make a 100 mM stock solution. |
| Storage & Handling | Store lyophilized powder at -20°C. Once reconstituted, store aliquoted at -80°C. Use reconstituted material within 6 months to avoid loss of potency. Avoid freeze thaw cycles. |
| Application | Cell Culture - Verified |
| Recommended Usage | 2-Deoxy-D-glucose can be used for inhibition of glycolysis. For primary immune cells (e.g. PBMCs or splenocytes) a range of 2.5 – 10.0 mM is recommended. It is recommended that the reagent be titrated for each experiment to determine optimal performance. |
| Structure | C6H12O5. 164.16 g/mol |
| Function | Glycolysis inhibitor |
| Antigen References | Arguello, et al. 2020. Cell Metabolism. 32:1063-1075. Traba, et al. 2016. J Vis Exp. 117:54918. Li, et al. 2019. J Cell Phys. 234:11. Lin, et al .2017. Oncotarget. 8:110426. Repas, et al. 2022. Cancers. 14:1343. |
| Gene ID | NA |
| Regulatory Status | RUO |
| Other Names | Glycolysis Inhibitor, 2-Deoxyglucose, 2-Deoxy-D-arabinohexose, C6H12O5 |
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