Biolegend, 446307, LEGEND MAX™ Human IL-29 (IFN-λ1) ELISA Kit

Interleukin-29 (IL-29, IFN-λ1) is a member of the type III interferon family of cytokines. It shares a high degree (~80%) of amino acid sequence homology with both IL-28A (IFN-λ2) and IL-28B (IFN-λ3). IL-29 is produced by human peripheral blood mononuclear and dendritic cells in response to viral infection, TLR stimulation, or other type I IFN agonists. IL-29 has been demonstrated to upregulate MHC I expression on target cells; in addition, IL-29 also mediates the antiviral immune response to several viruses including Hepatitis B (HBV), Hepatitis C (HCV), and Human Immunodeficiency Virus (HIV). Increased serum levels of IL-29 have also been reported in Hashimoto’s thyroiditis patients. The BioLegend LEGEND MAX™ Human IL-29 (IFN-λ1) ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a polyclonal goat anti-human IL-29 capture antibody. The detection antibody is a biotinylated polyclonal goat anti-human IL-29 antibody. This kit is specifically designed for the accurate quantitation of human IL-29 (IFN-λ1) from cell culture supernatant, serum, plasma, and other biological fluids. This kit is analytically validated with ready-to-use reagents.