Biolegend, 447907, LEGEND MAX™ Mouse IFN-α1 ELISA Kit

IFN-α1 is a chemokine produced by dendritic cells, lymphocytes, macrophages and other cells in response to infection. It is expressed in the thymus, placenta, and the spleen, and is produced primarily by hematopoietic cells, in particular plasmacytoid dendritic cells found in the peripheral lymphoid organs. IFN-α1 binds to IFNAR, causing a cascade that promotes expression of IFN stimulated genes, which have anti-viral, anti-tumor, anti-proliferative, and immunomodulatory functions. The BioLegend LEGEND MAX™ Mouse IFN-α1 ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is precoated with a mouse monoclonal anti-mouse IFN-α1 antibody. The detection antibody is a biotinylated polyclonal anti-mouse IFN-α1 antibody. This kit is specifically designed for the accurate quantitation of mouse IFN-α1 in cell culture supernatant, serum and plasma. This kit is analytically validated with ready-to-use reagents.