Biolegend, 448607, LEGEND MAX™ Human α-Synuclein (Colorimetric) ELISA Kit

α-Synuclein is a 140-amino-acids long neuronal protein that belongs to the Synuclein family, which also includes β-Synuclein and γ-Synuclein. At the cellular level, α-Synuclein primarily localizes in the synaptic terminals of neurons. However, it can also be found in other cell types such as red blood cells. Although the normal function of α-Synuclein is not fully understood, it was reported to have an important role in synaptic vesicle transport and membrane fusion. Moreover, the aggregate form of α-Synuclein is one of the major components of the inclusion bodies (Lewy bodies) inside nerve cells affected by the Parkinson’s disease and Lewy body dementias. The LEGEND MAX™ Human α-Synuclein (Colorimetric) ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with anti-human α-Synuclein monoclonal antibody. The detection antibody is a biotinylated anti-human α-Synuclein monoclonal antibody. This kit is specifically designed for the accurate quantitation of human α-Synuclein from cerebrospinal fluid, serum, plasma, urine, tissue lysate, and cell culture sup. It is analytically validated with ready-to-use reagents.