Biolegend, 449007, LEGEND MAX™ Human Amyloid Beta (1-40) ELISA Kit

Human amyloid beta (1-40) is a peptide fragment implicated in the onset and progression of Alzheimer’s disease, due to its presence in amyloid plaques that are a hallmark of the disease. This peptide, along with amyloid beta (1-42) and other amyloid isoforms, is generated from the cleavage of amyloid precursor protein (APP). Amyloid beta (1-40) and amyloid beta (1-42) are the two most common isoforms in the brain. While amyloid beta (1-40) is more prevalent, amyloid beta (1-42) is the major component of amyloid plaques. Nevertheless, amyloid beta (1-40) is relevant for Alzheimer’s research because the amyloid beta (1-42)/amyloid beta (1-40) ratio is an important diagnostic for the severity of Alzheimer’s disease. The BioLegend LEGEND MAX™ Human Amyloid Beta (1-40) ELISA Kit is a Sandwich Enzyme-Linked Immunosorbent Assay (ELISA) with a 96-well strip plate that is pre-coated with a mouse monoclonal anti-human amyloid beta (1-40) antibody. The detection antibody is a biotinylated mouse monoclonal anti-human amyloid beta (1-40) antibody. This kit is specifically designed for the accurate quantitation of human amyloid beta (1-40) in cerebrospinal fluid, serum, plasma, and other biological fluids. This kit is analytically validated with ready-to-use reagents.