Biolegend, 449104, ELISA MAX™ Deluxe Set Human Fibroblast Growth Factor 21

Human Fibroblast Growth Factor 21 (FGF-21) is a 187-amino acid protein with an approximate molecular weight of 20 kD. FGF-21 is a stress-inducible hormone mainly secreted by the liver that regulates nutrient and metabolic homeostasis but also by other tissues including adipocytes, pancreas, and skeletal muscle. It plays an important role in regulating hepatic oxidation of fatty acids and gluconeogenesis in response to fasting and known to induce positive metabolic functions that regulate insulin sensitivity. Research suggests that increased levels of FGF-21 are correlated with type 2 diabetes mellitus, nonalcoholic fatty liver disease, and obesity. BioLegend’s ELISA MAX™ Deluxe Set contains the components necessary for the accurate quantification of natural and recombinant Human FGF-21. The set is designed for cost-effective and accurate quantification of Human FGF-21 in cell culture supernatant, serum, heparin plasma, citrate plasma or other biological fluids. BioLegend’s ELISA MAX™ Deluxe Sets are sensitive, accurate, and robust.