Biolegend, 519508, PE/Cyanine7 anti-human CXCL10 (IP-10) Antibody
100tests
Catalog Number: 519508
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| Verified Reactivity | Human |
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| Reported Reactivity | Rhesus |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA) |
| Preparation | The antibody was purified by affinity chromatography and conjugated with PE/Cyanine7 under optimal conditions. |
| Concentration | Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.) |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | ICFC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Excitation Laser | Blue Laser (488 nm)Green Laser (532 nm)/Yellow-Green Laser (561 nm) |
Answer:PE/Cyanine7 Anti-Human CXCL10 (IP-10) Antibody, 519508.
Answer:Human CXCL10; PE/Cyanine7; Research antibody.
Answer:PE/Cyanine7 anti-human CXCL10 is a fluorescent antibody for detection of the chemokine CXCL10, also called IP-10, in compatible flow-cytometric immunoassays.
PE/Cyanine7 anti-human CXCL10 is a fluorescent antibody for detection of the chemokine CXCL10, also called IP-10, in compatible flow-cytometric immunoassays. CXCL10 is an interferon-inducible signaling molecule involved in leukocyte recruitment and inflammatory responses. The PE/Cyanine7 tandem conjugate enables inclusion of CXCL10 in multicolor assay panels using appropriate excitation and emission settings. Depending on the validated workflow, the reagent may support intracellular cytokine staining or other sample formats compatible with the specific clone. It is intended for research investigation of inflammatory signaling and immune responses. Instrument compensation and sample preparation should be optimized for the selected assay; vial volume and clone are not assumed here.
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| RRID | AB_2904432 (BioLegend Cat. No. 519507) AB_2904432 (BioLegend Cat. No. 519508) |
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| Structure | CXC chemokine family, 8.7 kD |
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| Distribution | Monocytes, endothelial cells, and fibroblasts |
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| Function | Interacts with CXCR3 and serves as a chemoattractant for T cells, dendritic cells, monocytes/macrophages, and NK cells |
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| Ligand/Receptor | CXCR3 |
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| Cell Type | B cells, Dendritic cells, Endothelial cells, Fibroblasts, Monocytes |
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| Biology Area | Cell Biology, Immunology, Innate Immunity, Neuroinflammation, Neuroscience |
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| Molecular Family | Cytokines/Chemokines |
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| Antigen References | 1. Luster AD, et al. 1987. Proc. Natl. Acad. Sci. USA 84:2868. 2. Kaplan G, et al. 1987. J. Exp. Med. 166:1098. 3. Sarris AH, et al. 1993. J. Exp. Med. 178:1127. |
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| Gene ID | 3627 |
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| UniProt | View information about CXCL10 on UniProt.org |
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| Clone | J034D6 |
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| Regulatory Status | RUO |
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| Other Names | Interferon gamma induced protein-10 (IP-10) |
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| Isotype | Mouse IgG2a, κ |
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