Biolegend, 570214, Cell-Vive™ GMP Recombinant Human IFN-γ (carrier-free)

Name: Cell-Vive™ GMP Recombinant Human IFN-γ (carrier-free)
Brand: Biolegend
SKU: 570214

25microg

Catalog Number: 570214

Pricing

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Category

Cell Lysis Buffers

Description

Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ plays a role in class I antigen presentation pathway by inducing catalytic proteasome subunit replacement with immunoproteasome subunit. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells. BioLegend Cell-Vive™ GMP Recombinant proteins are manufactured and tested in accordance with USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and Ph. Eur. Chapter 5.2.12 in a dedicated GMP facility compliant with ISO 13485:2016. Specifications and processes include:

Specifications

General

Source	Human IFN-γ, amino acids Gln24-Gln166 (Accession # NM_000619) was expressed in E. coli.
Molecular Mass	The 144 amino acid N-terminal methionylated recombinant protein has a predicted molecular mass of 16,907 Da. The DTT-reduced protein and the non-reduced protein migrate at approximately 17 kDa by SDS-PAGE.
N-terminalSequence Analysis	Met-Gln-Asp-Pro-Tyr-Val-Lys-Glu-Ala-Glu
Purity	≥ 95%, as determined by Coomassie stained SDS-PAGE
Formulation	0.1 µm filtered protein solution is in 10 mM Sodium succinate, 5% Mannitol, pH 5.
Endotoxin Level	Less than or equal to 0.1 EU per μg protein as determined by the LAL method
Residual Host Cell Protein Content	≤ 1 ng/μg by ELISA
Concentration	500 µg/mL
Storage & Handling	Unopened vial can be stored between 2°C and 8°C for up to 2 weeks, at -20°C for up to six months, or at -70°C or colder until the expiration date. For maximum results, quick spin vial prior to opening. The protein can be aliquoted and stored at -20°C or colder. Stock solutions can also be prepared at 50 - 100 µg/mL in appropriate sterile buffer, carrier protein such as 0.2 - 1% endotoxin-free BSA or HSA can be added when preparing the stock solution. Aliquots can be stored between 2°C and 8°C for up to one week or stored at -20°C or colder for up to 3 months. Avoid repeated freeze/thaw cycles.

Ordering

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Biolegend, 570214, Cell-Vive™ GMP Recombinant Human IFN-γ (carrier-free)

Send an RFQ.

General

Notice

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