Biolegend, 601608, Alexa Fluor® 647 anti-human Cytokeratin 7 Antibody
100microg
Catalog Number: 601608
Send an RFQ.
Category
Loading…
| Verified Reactivity | Human |
|---|---|
| Antibody Type | Monoclonal |
| Host Species | Rat |
| Immunogen | Human KRT7 peptide (446-462) conjugated to KLH. |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions. |
| Concentration | 0.5 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | ICC - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by immunocytochemistry. For immunocytochemistry, a concentration range of 0.5 - 2.0 μg/ml (1:250-1:1000 dilution) is recommended. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
| Excitation Laser | Red Laser (633 nm) |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:
Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.
| Application Notes |
|---|
| This antibody does not react with mouse (in-house tested). Additional reported applications (for the relevant formats) include: spatial biology (IBEX)1,2. |
| Application References(PubMed link indicates BioLegend citation) | Radtke AJ, et al. 2020. Proc Natl Acad Sci USA. 117:33455-33465. (SB) PubMed Radtke AJ, et al. 2022. Nat Protoc. 17:378-401. (SB) PubMed |
|---|
| RRID | AB_2728460 (BioLegend Cat. No. 601607) AB_2728461 (BioLegend Cat. No. 601608) |
|---|
| Structure | Type II cytokeratin. 469 amino acids with a predicted molecular weight of 51 kD. |
|---|
| Distribution | Cytoplasm. |
|---|
| Function | KRT7 is a type II keratin, involved in the translational regulation of the human papillomavirus type 16 E7 mRNA. |
|---|
| Interaction | KRT7 interacts with EIF3S10, HPV16 E7, and GPER1. |
|---|
| Biology Area | Cell Biology, Cell Motility/Cytoskeleton/Structure, Neuroscience, Neuroscience Cell Markers |
|---|
| Molecular Family | Intermediate Filaments |
|---|
| Antigen References | 1. Tajima Y, et al. 2017. Sci Rep. 7:40684. 2. Huang B, et al. 2016. Oncogene. 35:4927. 3. Szponar A, et al. 2012. Virchows Arch. 460:423. 4. Sano M, et al. 2010. Int J Oncol. 36:321. |
|---|
| Gene ID | 3855 |
|---|
| UniProt | View information about Cytokeratin 7 on UniProt.org |
|---|
| Clone | W16155A |
|---|
| Regulatory Status | RUO |
|---|
| Other Names | Keratin type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Type-II keratin Kb7, Sarcolectin, SCL, Cytokeratin 7, Keratin 7 |
|---|
| Isotype | Rat IgG2a, κ |
|---|
