Biolegend, 740532, LEGENDplex™ Human B Effector 1/2 (Be1/2) Panel (9-plex) with Filter Plate

Human B cells, also known as B lymphocytes, are white blood cells that play key roles in adaptive immune responses. They function in the humoral immunity component of the adaptive immune system by secreting antibodies, and are also classified as professional antigen presenting cells (APCs). In addition, B cells also secrete an array of cytokines that mediate Th1- and Th2-like immune responses. The LEGENDplex™ Human B Effector 1/2 (Be1/2) Panel (9-plex) is a bead-based multiplex assay panel, which uses fluorescence-encoded beads suitable for use on various flow cytometers. This Panel focuses on 9 key targets involved in B effector 1 and 2 cell function: TNF-α, IL-13, IL-4, IL-6, IL-2, TNF-β, IFN-γ, IL-17A, and IL-12p70. It provides higher detection sensitivity and broader dynamic range than traditional ELISA methods. This panel has been validated for use on cell culture supernatant, serum, and plasma samples.