Biolegend, 740616, LEGENDplex™ Human HSC Myeloid Panel (7-plex) with Filter Plate

Hematopoietic stem cells (HSCs) are located in the red bone marrow, and differentiate to give rise to myeloid, erythroid, and lymphoid lineages of cells which can further differentiate into specialized blood cells. The differentiation of HSCs into specialized cells is orchestrated by a complex interplay between cytokines, growth factors, and chemokines which are considered important lineage-specific markers. The LEGENDplex™ Human HSC Myeloid Panel (7-plex) is a bead-based multiplex assay panel, which uses fluorescence-encoded beads suitable for use on various flow cytometers. This Panel focuses on 7 key targets involved in the differentiation of myeloid precursor cells into monocytes, macrophages, neutrophils, eosinophils, and basophils: IL-3, IL-34, M-CSF, GM-CSF, SCF, FLT3L, and CXCL12 (SDF1). It provides higher detection sensitivity and broader dynamic range than traditional ELISA methods. This panel has been validated for use on cell culture supernatant, serum, and plasma samples.