Biolegend, 741395, LEGENDplex™ Rat Inflammation Panel (13-plex) w/ FP V02

Inflammation is a major part of the immune response to infection or tissue injury. It is mediated by various cytokines and chemokines. Inappropriate activation of inflammatory responses is the underlying cause of many common diseases and inflammatory reactions. Therefore, accurate measurement of inflammatory cytokines is important for understanding the immune responses and disease processes. The LEGENDplex™ Rat Inflammation Panel V02 is a bead-based multiplex assay panel, suitable for use on various flow cytometers. This panel allows simultaneous quantification of 13 rat cytokines, including IL-1α, IL-1β, IL-6, IL-10, IL-12p70, IL-17A, IL-18, IL-33, CXCL1/KC, CCL2/MCP-1, GM-CSF, IFN-γ and TNF-α. Most of cytokines in this panel are produced by innate immune cells, linking the innate and adaptive immunity with other cells. This assay panel provides higher detection sensitivity and broader dynamic range than the traditional ELISA method. The panel has been validated for use on cell culture supernatant, serum and plasma samples.