Biolegend, 741617, LEGENDplex™ Hu Apolipoprotein (Apo) Panel (8-plex) w/VbP

Apolipoproteins (Apo) are proteins that bind to lipids to form lipoproteins, whose main function is to transport lipids. Apolipoproteins are important in maintaining the structural integrity and solubility of lipoproteins and play important roles in lipoprotein receptor recognition and the regulation of certain enzymes in lipoprotein metabolism. There are six major classes of Apo: A, B, C, D, E and H. The Apo system is complex and the balance between Apo proteins is important. Disturbance of the balance may be associated with diseases such as Alzheimer’s Disease, Hyperlipoproteinemia, heart disease, atherosclerosis, diabetes, and cancer. The Human Apo panel is a multiplex bead-based assay panel, using fluorescence–encoded beads suitable for use on various flow cytometers. This panel allows simultaneous quantification of 8 human Apo proteins, including Apo AI, CII, D, E, E4, H, J and M. This assay panel provides broader dynamic ranges than traditional ELISA methods. This panel has been validated for use on serum and plasma samples.