Biolegend, 853712, Alexa Fluor® 488 anti-Synapsin I/II/III Antibody
100microg
Catalog Number: 853712
Send an RFQ.
Category
Loading…
| Verified Reactivity | Human, Rat |
|---|---|
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Immunogen | Recombinant protein corresponding to amino acids 362-450 of human Synapsin I |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions. |
| Concentration | 0.5 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | IHC-P - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
| Excitation Laser |
Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
For quotation requests, please send an RFQ from website or contact:
Please send inquiries directly to us in the “To” field. Emails sent via BCC, mass mailing, or with unrelated recipients may be automatically filtered and will not be processed.
| Blue Laser (488 nm) |
| RRID | AB_2814568 (BioLegend Cat. No. 853711) AB_2814569 (BioLegend Cat. No. 853712) |
|---|
| Structure | Synapsin I is a 704 amino acid protein with an apparent molecular mass of ~74 kD. Synapsin II is a 582 amino acid protein with an apparent molecular mass of ~63 kD. Synapsin III is a 580 amino acid protein with an apparent molecular mass of ~63 kD. |
|---|
| Distribution | Tissue distribution: Mainly in the central nervous system. Also expressed in testis. Cellular distribution: Cytosol, nucleus, and plasma membrane. |
|---|
| Function | Synapsins are involved in the regulation of synaptic vesicle fusion and neurotransmitter release at the presynaptic terminals. |
|---|
| Interaction | CAPON (Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein), PKA |
|---|
| Cell Type | Neurons |
|---|
| Biology Area | Cell Biology, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Synaptic Biology |
|---|
| Molecular Family | Presynaptic proteins, Synaptic Vesicle Trafficking/Endocytosis |
|---|
| Antigen References | Greengard P, et al. 1993. Science. 259(5096):780 Milovanovic D, et al. 2017. Neuron. 93(5):995 Evergren E, et al. 2007. J. Neurosci. Res. 85(12):2648 |
|---|
| Gene ID | 685368548224 |
|---|
| UniProt | View information about Synapsin I/II/III on UniProt.org |
|---|
| Clone | A17080A |
|---|
| Regulatory Status | RUO |
|---|
| Other Names | SYN, Synapsin, Synapsin I, Synapsin II, Synapsin III |
|---|
| Isotype | Mouse IgG2b, κ |
|---|
