Biolegend, 862207, Alexa Fluor® 488 anti-Myelin Protein Zero Antibody
25microg
Catalog Number: 862207
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| Verified Reactivity | Human, Mouse, Rat |
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| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Formulation | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Preparation | The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions. |
| Concentration | 0.5 mg/ml |
| Storage & Handling | The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze. |
| Application | IHC-P - Quality tested |
| Recommended Usage | Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 2.0 - 10 µg/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application. * Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm. Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses |
| Excitation Laser | Blue Laser (488 nm) |
| Application References(PubMed link indicates BioLegend citation) |
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| Yoshimura K, et al. 1996. Neurosci Res. 25(1):41 (WB, IHC, ELISA) |
| RRID | AB_2814591 (BioLegend Cat. No. 862207) AB_2814592 (BioLegend Cat. No. 862208) |
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| Structure | MPZ is a 248 amino acid protein with an apparent molecular mass of ~ 28 kD. |
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| Distribution | Tissue Distribution: Peripheral nervous system Cellular Distribution: Plasma membrane, extracellular, endoplasmic reticulum, and lysosome |
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| Function | MPZ is an adhesion molecule involved in the formation of myelin sheath in the peripheral nervous system. |
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| Interaction | Forms homodimer and homotetramer |
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| Biology Area | Neurodegeneration, Neuroscience Cell Markers |
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| Molecular Family | Adhesion Molecules |
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| Antigen References | Chiò A and Lauria G. 2016. Lancet Neurol. 15(1):12 Brennan KM, et al. 2015. Neurosci Lett. 596:14 Tazir M, et al. 2014. J Neurol Sci. 347(1-2):14 |
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| Gene ID | 43591752824564 |
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| UniProt | View information about Myelin Protein Zero on UniProt.org |
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| Clone | 58A |
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| Regulatory Status | RUO |
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| Other Names | MPZ, Myelin Protein Zero |
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| Isotype | Mouse IgG2b, κ |
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