Cytiva, 17548203, LambdaFabSelect, 1 L

Name: LambdaFabSelect, 1 L
Brand: Cytiva
SKU: 17548203

Catalog Number: 17548203

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Category

Affinity Tag Purification Resins

Pack Size1 L

TagsChromatography resins Chromatography products Affinity antibody resin

CollectionsCytiva Chromatography Columns, Resins & Lab Glassware Cytiva Protein Analysis Equipment & Supplies Collection

Description

LambdaFabSelect is an affinity resin designed for the purification of human lambda Fab fragments, with high binding capacity, purity, and yield.
Rigid agarose base matrix allows high flow rates and processing of large sample volumes for increased throughput
Non-mammalian derived product reduces regulatory concerns in the production of Fabs for clinical applications
LambdaFabSelect is an affinity resin designed for the purification of human lambda Fab fragments. The ligand binds to the constant region of the light chain enabling an efficient capture step for human antibody fragments such as Fabs with high purity and yield.
Antibody fragments, especially Fabs, are getting increased attention as potential biopharmaceuticals because they have some advantages over monoclonal antibodies (Mabs). For example, Fabs show improved pharmacokinetics for tissue penetration and can bind to targets inaccessible to conventional antigen-binding sites.
The product is a part of Cytiva's Custom Designed resins program.

Specifications

General

Chromatography technique	Antibody affinity chromatography
Binding Capacity/ml Chromatography Medium	Approximately 20 mg Fab/mL of resin
BioProcess resin	No
Chemical stability	Stable to commonly used aqueous buffers: 6 M urea, 6 M guanidine hydrochloride, 70 % ethanol, 30 % isopropanol
Ligand	Recombinant protein (M r 13 000), produced in S. cerevisiae , with affinity for the constant domain of the immunoglobulin lambda light chain
Ligand density	Approx. 7 mg/ml of medium
Matrix	Highly cross-linked agarose
Order Information	This product is part of our Custom Designed Media program and not yet a standard product. If you are interested in large-scale quantities, please contact your local Cytiva representative.
Particle size, d 50V	~75 µm
Pressure/Flow Specification	300 kPa at 600 cm/h, 1 m diameter column, 20 cm bed height
Storage	2 to 8°C, 20% Ethanol
pH stability, CIP	2–12
pH stability, operational	3–10

Ordering

Notice

Unless otherwise stated, the minimum order amount is USD 1,000.
For orders below USD 1,000, an additional handling fee may apply, or we may arrange local delivery / local handover where available.
All quotations are subject to final confirmation, including product availability, lead time, batch information, shipping cost, and applicable export or handling requirements.
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