Lonza, CC-2540S, NHBE-Human Bronchial/Tracheal Epithelial Cells for B-ALI TM Culture

Product Overview Normal and Diseased Bronchial Epithelial (NHBE and DHBE) cells are isolated from epithelial lining of airways above bifurcation of the lungs. CC-2540S are NHBEs suitable for air-liquid interface cell culture and are guaranteed for differentiation marked by cilia formation, mucin production, and TEER levels. All cryopreserved human bronchial epithelial cells are guaranteed through 15 population doublings. Cells test negative for mycoplasma, bacteria, yeast, and fungi. HIV-1, hepatitis B and hepatitis C are not detected for all donors and/or cell lots. A Certificate of Analysis is provided for each cell lot purchased. Select Applications with Lonza's Human Bronchial Epithelial Cells "A Rotating Bioreactor for Scalable Culture and Differentiation of Respiratory Epithelium”. Respiratory epithelium is difficult to grow as it requires a well-maintained polarizing air‐liquid interface (ALI) to maintain differentiation. Raredon et al. describe a scalable and easy method to conduct air-liquid interface with Lonza's bronchial epithelial cells guaranteed for ALI differentiation (Cat. No. CC-2540S). Request More Info
Storage and Content 1 x cryopreserved ampoule containing ≥500,000 cells