Lonza, CC-2554, HRCE – Human Renal Cortical Epithelial Cells

Product Overview Lonza's Human Renal Cells include cells isolated from various normal human kidney tissue specific to each cell type. Human Renal Proximal Tubule Cells are isolated from the proximal tubule and are ideal for drug transporter studies. Human Renal Epithelial Cells (HRE) are comprised of cells from the cortex and glomerular region. Human Renal Cortical Cells (HRCE) are from proximal and distal tubules. Human Mesangial Cells (HMC) are isolated from the renal glomerulus and modified smooth muscle cells between capillaries. Renal epithelial cells display a polarized morphology, which is essential for their function. They reabsorb nearly all of the glucose and amino acids in the glomerular filtrate, while allowing other substances of no nutritional value to be excreted in the urine. Physiological processes like osmoregulation and excretion can be studied with renal epithelial cells in vitro. Human renal epithelial cells are also capable of internalizing bacteria and are located near injury sites in a variety of congenital, metabolic and inflammatory diseases. Request More Info
Benefits Guaranteed through 15 population doublings Test negative for mycoplasma, bacteria, yeast, and fungi HIV-1, Hepatitis B and Hepatitis C are not detected for all donors and/or cell lots A Certificate ofAnalysis is provided for each cell lot purchased
Storage and Content 1 x Cryopreserved ampule of HRCE containing ≥500,000 cells