Merck, 11702-25G, Bacitracin

Name: Bacitracin
Brand: Merck
SKU: 11702-25G

Size:25 g, Altracin, Bacitracin A, from Bacillus licheniformis, ≥65 IU/mg

Available Catalog Numbers

11702-25G 11702-5G

Catalog Number: 11702-25G

Pricing

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Category

Antibiotics & Antimycotics

Pack Size25 g

TagsCell Culture & Analysis Cell Culture Supplements & Reagents Antibiotics

CollectionsMerck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Chemical structure: peptide
Application
Bacitracin is used to study disruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is also used to study the biosynthesis of sterols and squalene.
Bacitracin has been used:
as a protease inhibitor
as a control antibiotic
for the calibration in size exclusion chromatography

Biochem/physiol Actions
Bacitracin has been shown to decrease vancomycin-resistant Enterococcus faecium population in intestine.
Bacitracin is a peptide antibiotic.
Antimicrobial spectrum: Gram-positive bacteria.
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.
Packaging
5G, 25 G
Other Notes
Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.

Specifications

General

color
NACRES	NA.85
PubChem Substance ID	57646949
UNSPSC Code	51282002
EC Number	215-786-2
MDL number	MFCD00062640
InChI	1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-/m0/s1
InChI key	CLKOFPXJLQSYAH-RNHDWVCBSA-N
SMILES string	[H]N1[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)C3CSC(=N3)C(N)C(C)CC)[C@@H](C)CC)C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](Cc4ccccc4)C1=O
biological source	Bacillus licheniformis
form	powder
specific activity	≥65 IU/mg

Ordering

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Merck, 11702-25G, Bacitracin

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