Merck, 136581-5G, 1,5-Diazabicyclo[4.3.0]non-5-ene

General description
DBN is a strong base widely used as a catalyst in organic synthesis to facilitate Michael additions and aldol condensations.
Application
1,5-Diazabicyclo[4.3.0]non-5-ene (DBN) can be used as:
A reagent for the synthesis of β-carbolines from tetrahydro-β-carbolines via dehydrogenative/decarboxylative aromatization.
A nucleophilic organocatalyst in the regioselective C-acylation of pyrroles and indoles by Friedel−Crafts acylation reaction.
A superbase in the formulation of a ternary liquid-liquid phase changing system, along with hexadecane and hexanol, to capture hydrogen sulfide gas.
A base for the preparation of 1H-quinazoline-2,4-diones from 2-aminobenzonitriles using supercritical carbon dioxide as a reactant and a solvent.
A catalyst for the synthesis of benzothiazolones by the reaction between 2-aminothiophenols and CO₂ by cyclocarbonylation reaction via C-S bond formation.