Merck, 142077-100G, 2,2,2-Trichloroethyl chloroformate

General description
2,2,2-Trichloroethyl chloroformate (TrocCl) serves as a versatile reagent used for selective acylation and dealkylation in organic synthesis. It is used in regio, chemo, and stereoselective synthesis.
Application
Protecting reagent for aliphatic and aromatic hydroxyl and amino groups.
2,2,2-Trichloroethyl chloroformate was used as derivatizing reagent in gas chromatographic/mass spectrometric determination of a large range of amphetamine-related drugs and ephedrines in plasma, urine and hair samples.
It was used as starting reagent during the synthesis of 6-Nor-9,10-dihydrolysergic acid methyl ester.
It was used as reagent during N-demethylation of dextromethorphan.
It was used as protecting reagent for aliphatic and aromatic hydroxyl and amino groups.