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Zirconocene dichloride serves as a catalyst, enabling efficient synthesis of pyrrole with high yields and simplifies the purification process economically.
ApplicationUsed to promote greener amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents.
Direct amide formation from unactivated carboxylic acids and aminesUseful in the synthesis of a wide range of early-transition-metal complexes and organometallic compounds.