Description
General description
Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state (aggregation number: 11; CMC: 8 mM; micellar weight: 9960). Capable of solubilizing the opiate receptor to a state exhibiting reversible binding of opiates. Has a higher solubility than CHAPS because of its more polar head group.
Preparation Note
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 3 days at 4°C.
Other Notes
Simonds, W.F., et al. 1980. Proc. Natl. Acad. Sci. USA77, 4623.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)