Merck, 345830-100UG, Galectin-3, Human, Recombinant, E. coli

General description
Recombinant, human galectin-3 expressed in and purified from E. coli. Galectin-3 is a member of the β-galactoside-binding animal lectins. It has been implicated to be involved in various immunological processes, pre-mRNA splicing, cell adhesion, and tumor invasion. Levels of galectin-3 have been reported to be elevated in several metastatic cancers.
Physical form
Lyophilized from diH₂O.
Preparation Note
Following reconstitution refrigerate (4°C). Stock solutions containing lactose are stable for up to 6 months at 4°C. Following dialysis and removal of lactose, stock solutions are stable for up to 4 days at 4°C.
Reconstitute in sterile PBS. For use in carbohydrate binding studies, lactose should be removed by dialysis.
Other Notes
Legendre, H., et al. 2003. Mod. Pathol.16, 491.
Maeda, M., et al. 2003. J. Biol. Chem.278, 18938.
Stock, M., et al. 2003. J. Biol. Chem.278, 17360.
Hirabayashi, J., et al. 2002. Biochim. Biophys. Acta1572, 232.
Iurisci, I., et al. 2000. Clin. Cancer Res.6, 1389.
Oda, Y., et al. 1991. Gene99, 279.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)