Merck, 361798-100ML, Lithium diisopropylamide solution

General description
Lithium diisopropylamide solution (LDA) is a sterically hindered non-nucleophilic strong base widely used in organic synthesis.
Application
Lithium diisopropylamide solution (LDA) can be used:
As an initiator in the anionic polymerization of D,L-lactide and methyl methacrylate.
To facilitate ester enolization.
To convert carboxylic acids to enediolate intermediates for preparing trifluoromethyl ketones.
In ortho-lithiation of arylsulfonyloxazolidinones to prepare N-substituted saccharin analogs.
To catalyze ortholithiation and Fries rearrangement of aryl carbamates.
As a promoter in the isomerization of allylic ethers to (Z)-propenyl ethers.

Packaging
The 25 mL Sure/Seal™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.
Legal Information
Sure/Seal is a trademark of Sigma-Aldrich Co. LLC