Merck, 383120-500G, Sulfamic acid

General description
Sulfamic acid (H₂NSO₃H) is widely used inorganic compound. It exists in zwitterionic form and neutral forms. Zwitterionic form has been reported to be is more stable than neutral form. Its industrial applications have been reported. It has various organic synthesis applications.
Sulfamic acid is a strong inorganic acid. It is a hypochlorite scavenger. The ability of sulfamic acid to reduce nitrate to nitrogen gas under acidic condition has been utilized to denitrify nitrate-rich wastewater along with zinc powder.
Application
Sulfamic acid (H₂NSO₃H) may be used in the following studies:
As catalyst in the synthesis of aryl-14H-dibenzo[a.j]xanthenes.
As green catalyst for the preparation of amide from ketoxime.
As ammonia equivalent in the regioselective synthesis of primary allylic amines, via allylic substitution reactions.
Synthesis of polysubstituted quinolones.

Sulfamic acid may be used in the following processes:
As a titrant in the determination of the burette injection volume and chemical calibration factor.
To neutralize excess nitrous acid in the colorimetric paracetamol assay by modified Glynn and Kendal colorimetric method.
To prevent endogenous mercury (Hg) loss during the urine Hg measurement by inductively coupled plasma mass spectrometry (ICP-MS) method.
As an acid catalyst and a hypochlorite scavenger in the chlorite oxidation of dialdehyde cellulose (DAC).
As a heterogeneous catalyst in the synthesis of polyhydroquinoline derivatives by Hantzsch condensation reaction.
As catalyst in the degradation of bamboo fiber to 5-hydroxymethylfurfural (HMF).
As an acid reagent in the determination of silicates in water samples based on centrifugal microfluidics.
As catalyst in the synthesis of deazaoxaflavin at room temperature.