Merck, 5120-OP, Guanidine Isothiocyanate

General description
Protein denaturant used to inactivate RNases during isolation of RNA from cell lysates. Molecular biology grade.

Specifications:
A (280 nm, 70%, water): ≤0.8AU
Assay: ≥99.0%
DNase: None detected
Melting point: 118-121°C
Protease: None detected
RNase: None detected
Solubility (70%, water): To pass test

Intended for laboratory and manufacturing use only. Not for drug, food, or household use.
Application

Collection and transportation of SARS-CoV-2 and influenza A virus diagnostic samples: Optimizing the usage of guanidine-based chaotropic salts for enhanced biosafety and viral genome preservation: This study emphasizes the critical role of guanidine isothiocyanate in the preservation of viral genomes during the collection and transport of diagnostic samples, thereby enhancing biosafety protocols in molecular biology applications (Komu JG et al., 2024).

How to better select SARS-CoV-2 preservation solution of virus nucleic acid testing: Focuses on optimizing viral RNA preservation using solutions containing guanidine isothiocyanate, contributing to more accurate diagnostics in virology (Duan X et al., 2023).

Visual Detection of Chicken Adulteration Based on a Lateral Flow Strip-PCR Strategy: Demonstrates the application of guanidine isothiocyanate in developing rapid diagnostic tools for food safety, enhancing the detection of adulterants in chicken products (Xu H et al., 2022).

Using discrete event simulation to optimize nucleic acid testing process for coronavirus disease 2019 (COVID-19): Describes how guanidine isothiocyanate enhances the efficiency of COVID-19 testing processes, aiding in faster diagnosis and better pandemic management (Guan W et al., 2022).

Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
OMNIPUR is a registered trademark of Merck KGaA, Darmstadt, Germany