Merck, 657697-100MG, (1R,1′R,2S,2′S)-DuanPhos

General description
(1R,1′R,2S,2′S)-DuanPhos is an electron-rich chiral phosphine ligand mainly for transition metal catalyzed asymmetric hydrogenation.
Application
Chiral Quest Phosphine Ligands for Asymmetric Hydrogenation

Catalytic ligand used for:
Stereoselective synthesis of cyano-substituted dihydropyrroles by annulation of cyanoallenes
Rhodium-catalyzed intermolecular enantioselective hydroacylation of alkynes to give alpha- and beta-substituted unsaturated ketones by kinetic resolution
Stereoselective preparation of β-amino nitriles via rhodium-catalyzed asymmetric hydrogenation of amino acrylonitriles
Stereoselective preparation of anti-1,3-amino alcohols via rhodium-catalyzed asymmetric hydrogenation of β-ketoenamide intermediates
Stereoselective preparation of acetylaminoindane via rhodium-catalyzed asymmetric hydrogenation of acetylaminoindene