Merck, 701998-1G, [1,1′-Bis(di-cyclohexylphosphino)ferrocene]dichloropalladium(II)

General description
We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives. This product falls under category 12 PAP and aligns with the Green Chemistry Principle of Catalysis. It is an air-stable ferrocenyl bisphosphine–Pd complex that catalyzes α-arylation of ketones with aryl chlorides/bromides, enabling C–C bond formation under mild conditions. Click here for more information.
Application
1,1′-Bis(di-cyclohexylphosphino)ferrocene]dichloropalladium(II) or (Pd(dcpf)Cl₂) can be used as a catalyst in the synthesis of:
α, β-unsaturated amides by hydroaminocarbonylation of alkynes with tertiary amines.
Quinazoline derivatives via Suzuki-Miyaura coupling reaction between of quinazolines containing unprotected NH₂ group and arylboronic acids.
α-aryl carbonyl compounds by α-arylation of ketones with aryl chlorides and aryl bromides.