Merck, 77253-10ML, Heptafluorobutyric anhydride

General description
Heptafluorobutyric anhydride is a perfluoroacylated acylation reagent, that forms stable, volatile derivatives with alcohols, amines, and phenols. It is majorly used to prepare electron-capturing derivatives for GC/electron capture detection. It is generally used with an acid scavenger, to help drive the reaction to completion and to prevent column damage from acidic by-products of the derivatization reaction. It is also used for the frequent testing of drugs of abuse such as, amphetamines and phencyclidine by GC-MS technique.
Application
Learn more in the Product Information
Packaging
Clear borosilicate glass, high hydrolytic resistance (Type I)
Analysis Note
Suitable for derivatization of aldosterone, digoxin, digitoxin and metabolites, estradiol, postaglandins F₁α and F₂α,3-oxo-Δ⁴-steroids, steroids and testosterone.
Other Notes
Reagent for 3-enol heptafluorobutyrate, heptafluorobutyrate, heptafluorobutyryl, 17-heptafluorobutyryl and 17-heptafluorobutyrate.
HFAA acylates amines, amino acids and other compounds. HFBA derivatives are highly volatile: used in GC separation
Legal Information
LiChropur is a trademark of Merck KGaA, Darmstadt, Germany