Merck, 850371P-500MG, 22:0 PC

General description
Phosphatidylcholines (PCs) are amphipathic molecules, that are mainly located on the outer leaflets of the biological membrane bilayer. Approximately 40–50% of the total cellular phospholipids consists of phosphatidylcholine.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.
Application
22:0 PC may be used:
to study its effects on non-amyloidogenic processing of amyloid precursor protein (APP)/α-secretase activity
to prepare a lipid monolayer to study whether ligand is specifically targeted to domains containing Cu(II)-iminodiacetate lipid (Cu-PSIDA)
as a lipid standard for the quantification of lipid species from lipid droplets by hydrophilic interaction liquid chromatography-high performance liquid chromatography (HILIC-HPLC)

Biochem/physiol Actions
Phosphatidylcholines (PCs) can serve as lung surfactant.
Packaging
20 mL Clear Glass Screw Cap Vial (850371P-1g)
20 mL Clear Glass Screw Cap Vial (850371P-500mg)
5 mL Amber Glass Screw Cap Vial (850371P-25mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC