Merck, 906506-1KT, HLAM-AβIδ1MεLVproSTγ-13CH3 Methyl Labeling Kit

General description
HLAM-AβIδ¹MεLVproSTγ-¹³CH₃ kit has ¹³CH₃isotopomer precursors and contains protocol instructions for creation of isotopically-labeled proteins.
Application
For detection of long-range nOes or for the NMR study of large proteins
HLAM-AβIδ¹MεLVproSTγ-¹³CH₃ is an optimized kit used to produce proteins with ¹³CH₃ isotopomer on methyl groups of alanine, isoleucine, methionine, leucine and threonine residues. This kit has been tested with protein isotopic labeling in E. coli. It can be used to study large molecular system and complex protein structure in NMR spectroscopy along with other spectroscopic approaches. The sensitivity of the isotopomer can be enhanced by three-fold multiplicity. This kit can also be used to simplify crowded spectra to provide specific probes of dynamic and structural studies in solid state NMR spectroscopy.
Packaging
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service. jj