Merck, 923443-500MG, PhMPhos

General description
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Application
PhMPhos is an unsymmetrical ferrocene-based phosphine ligand. The MPhos series of ligands are unsymmetrical diphosphino-ferrocenes bearing a bulky adamantyl group. Pd catalysts containing PhMPhos can be used for a variety of cross-coupling transformations, including Suzuki coupling, C-P coupling, and Csp²-Csp³ coupling. Demonstrated Csp²-Csp³ couplings include Murahashi-Feringa Coupling (Alkyl-Li), Kumada-Corriu coupling (Alkyl-MgX), Negishi coupling (Alkyl-ZnX) and Suzuki–Miyaura coupling (Alkyl-B(OR₂)).

Learn more about MPhos ligands and catalysts
Other Notes
Tunable Unsymmetrical Ferrocene Ligands Bearing a Bulky Di-1-adamantylphosphino Motif for Many Kinds of Csp²–Csp³ Couplings