Description
Application
NanoFabTx™ Natural Folate Lipid Mix is a ready-to-use nanoformulation lipid mixture for the synthesis of folate-functionalized liposomes. This lipid mix enables users to encapsulate a wide variety of therapeutic drug molecules for targeted drug delivery applications without the need for lengthy trial-and-error optimization.
NanoFabTx™ Natural Folate Lipid Mix is a lyophilized, curated, lipid mixture containing rationally selected lipids in precise ratios that have been optimized to achieve liposomes of approximately 100nm in diameter. The synthesized folate-functionalized liposomes can be used to selectively target cells which overexpress folate receptors such as HeLa cells and delivery hydrophilic or hydrophobic drugs, including therapeutics that are thermo-sensitive.
Features and Benefits
A ready-to-use nanoformulation lipid blend for the synthesis of folate-functionalized liposomes without the need for high temepratures
Step-by-step protocols developed and tested by our formulation scientists
Flexible synthesis tool to create uniform and reproducible liposomes
Optimized to make liposomes around 100 nm with low polydispersity
Optimized lipid blend for folate-functionalized liposomes for therapeutic encapsulation
For microfluidic liposome synthesis of azide-functionalized liposomes, the NanoFabTx™- Natural Folate Lipid Mix can be used with the the NanoFabTx™Microfluidic - nano device kit (Cat.No. 911593). The NanoFabTx™Microfluidic - nano device kit includes the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).
Legal Information
NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
