Merck, 934119-50MG, Ovine collagen

General description
Collagen is a major component of the extracellular matrix (ECM) and offers low immunogenicity, a porous structure, good permeability, and biocompatibility to promote cell viability, adhesion, spreading, proliferation and differentiation.

Low endotoxin SPDP functionalized collagen derived from ovine can be used for the covalent conjugation with sulfhydryl-containing molecules. The primary amine groups (lysine residues) of the collagen are reacted with succinimidyl 3-(2-pyridyldithio)propionate (SPDP) to yield collagen derived with a cleavable disulfide bond. The cleaved linker can react with other species containing containing free sulhydryl groups (i.e. cysteine residues) which are commonly found in many naturally occurring protein or peptide sequences.
Application

• 3D bioprinting
• Tissue engineering
• Drug delivery
• Regenerative medicine
• Cell culture, encapsulation, expansion and differentiation

Features and Benefits

• Certified Disease Free Sheep
• 93-97% Type I Collagen
• 3-7% Type III Collagen
• 99% Purity
• Prion Free

Legal Information
CollOvine is a trademark of OviGenex LLC