Merck, A111030-12X1G, DMT-dA(bz) Phosphoramidite

Name: DMT-dA(bz) Phosphoramidite
Brand: Merck
SKU: A111030-12X1G

Size:12 x 1 g, DMT-dA(bz) Amidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyadenosine, 3′-[2-cyanoethyl N, N-bis(1-methylethyl)phosphoramidite], N6-Benzoyl-5′-O-(4, 4′-dimethoxytrityl)-2′-deoxyadenosine-3′-O-[O-(2-cyanoethyl)-N, N′-diisopropylphosphoramidite], configured for ABI

Available Catalog Numbers

A111030-12X1G A111030-12X2G

Catalog Number: A111030-12X1G

Pricing

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Category

Nucleotides & Nucleosides

Pack Size12 x 1 g

TagsChemistry & Biochemicals Biochemicals Nucleosides & Nucleotides

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites :Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution,for standard base-protected oligonucleotides
The high coupling efficiency of Proligo′s DNA phosphoramidites leads tohigh-yield and high-quality oligonucleotides
The product belongs to ABI™ Synthesizers synthesizers.
Packaging
packaged in septum bottle
Legal Information
ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

Specifications

General

NACRES	NA.51
PubChem Substance ID	329770660
UNSPSC Code	41116107
MDL number	MFCD00036314
InChI	1S/C47H52N7O7P/c1-32(2)54(33(3)4)62(59-27-13-26-48)61-40-28-42(53-31-51-43-44(49-30-50-45(43)53)52-46(55)34-14-9-7-10-15-34)60-41(40)29-58-47(35-16-11-8-12-17-35,36-18-22-38(56-5)23-19-36)37-20-24-39(57-6)25-21-37/h7-12,14-25,30-33,40-42H,13,27-29H2,1-6H3,(H,49,50,52,55)/t40-,41+,42+,62?/m0/s1
SMILES string	COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)c5ccccc5)ncnc34)(c6ccccc6)c7ccc(OC)cc7
InChI key	GGDNKEQZFSTIMJ-AKWFTNRHSA-N
biological source	non-animal source (no BSE/TSE risk)
type	for DNA synthesis
product line	Proligo Reagents
assay	≥99% (31P-NMR)
form	powder or granules
technique(s)	oligo synthesis: suitable
impurities	≤0.3 wt. % water content (Karl Fischer)
color	white to off-white
solubility	water: 0.1 g/L at 20 °C
<i>λ</i>	conforms (UV/VIS Identity)
compatibility	configured for ABI

Ordering

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Merck, A111030-12X1G, DMT-dA(bz) Phosphoramidite

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