Merck, A8052-10MG, Arg-Gly-Asp

General description
Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand.
Application
Arg-Gly-Asp has been used:
to saturate the cell surface Arg-Gly-Asp (RGD) receptors and inhibit marrow stromal cell (MSC) attachment to peptide modified hydrogel
in adhesion assay
in inhibition assay to confirm the β1-integrin-dependency of cell adhesion
in textile fabrication and RGD textile functionalization
to engineer a population of human dermal fibroblasts with impaired migration
to modify glass substrate and evaluate the behavior of human bone marrow mesenchymal stem cells (hBM-MSCs)
in the cell culture of human mammary epithelial cells

Biochem/physiol Actions
Primary sequence involved with the binding of proteins to cell surfaces
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note
Tripeptide from the cell-attachment domain of fibronectin