Merck, A8185-5G, Ala-Gln

Application
Ala-Gln has been used:
as a supplement in NeuralQ™ medium
as a component in growth medium and incubation medium (IM) for retinal cell lines
for experimental treatment of retinal cell lines respectively

Biochem/physiol Actions
Alanyl-glutamine (Ala-Gln) is a dipeptide that is used as a substitute for glutamine in mammalian cell culture media, because of the instability of glutamine in solution and the formation of ammonia as a breakdown product of glutamine in solution, which can have deleterious effects on cells in culture. Ala-Glu is stable to heat sterilization and is less ammonia genic than glutamine, which contributes to its advantages as a media component. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.
Analysis Note
This product is cell culture tested (0.5 mg/ml) and insect cell culture tested (0.2 mg/ml). It is appropriate for use in cell culture and insect cell culture applications at 2-10 mM.
Legal Information
NeuralQ is a trademark of GlobalStem