Merck, A9062-1G, Adenosine 5′-triphosphate di(tris) salt hydrate

Application
Adenosine 5′-triphosphate di(tris) salt hydrate has been used:
to treat cells for Ca2+ influx measurements in stromal interaction molecule 1 knockout (STIM1−/−) mice and in vitro chemotaxis assay for microglial migration
supplemented in buffer C for mitochondrial respiratory control assay and complex V activity assay
in the inhibition of silver nano particles (AgNPs) on Na+/K+-ATPase activity

Biochem/physiol Actions
Adenosine 5′-triphosphate di(tris) salt dehydrate is useful in applications that require the absence of metals.
Adenosine 5′-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems
Disclaimer
Unstable: For maximum stability, store as frozen solution at pH 3.5 to 6.8.