Merck, A9187-1G, Adenosine 5′-triphosphate magnesium salt

Application
Adenosine 5′-triphosphate magnesium salt has been used:
as a supplement in intracellular medium for Ca2+ retention assay and fluorescence wide field imaging analysis
as a component in potassium methane sulfonate-based internal solution for in vitro electrophysiology of cortical neurons
as a component in action potential intracellular solution

Biochem/physiol Actions
Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.
P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems