Merck, A9771-5G, Albumin–fluorescein isothiocyanate conjugate

General description
Albumin makes up 60% of the plasma protein, which is produced by the liver. It regulates colloid osmotic pressure. Albumin is implicated in the transportation, distribution and metabolism of fatty acids, thyroid hormones and drugs. It reduces weight gain, blocks pulmonary edema, decreases ascites and lowers tissue edema.
Application
Albumin−fluorescein isothiocyanate conjugate has been used:
as a control to compare the intracellular delivery efficiency of proteins with or without carrier
for the fluorescent visualization of proteins and cells
as a blocking agent in ELISA
as a chemical for brain perfusion and fixation
for in vivo capillary–epithelial permeability experiment
for confocal microscopy of right ventricular (RV) vasculature in rats

Preparation Note
Prepared from crystallized and lyophilized albumin (A 4378).