Merck, B1638-5MG, Benzoyl coenzyme A lithium salt

General description
Benzoyl coenzyme A (Benzoyl CoA) is an intermediate in the CoA-dependent epoxide pathway, synthesized from benzoate in the presence of the enzyme benzoate-CoA ligase. It is further converted to 2,3-epoxybenzoyl-CoA and this step is catalyzed by benzoyl-CoA reductase (BoxA) and benzoyl-CoA oxygenase(BoxB).
Biochem/physiol Actions
Benzoyl coenzyme A (Benzoyl CoA) may be used in studies of benzoate metabolism. Benzoyl CoA is a component of benzoyl-coenzyme A (CoA) oxidizing epoxidase enzyme system BoxAB. Benzoyl CoA may also be used as a substrate for characterization of specific alcohol acyltransferases. Benzoyl-CoA may be used as a starter substrate for synthesis of biphenyl and dibenzofuran phytoalexins (polyketide derivatives).
Benzoyl coenzyme A (Benzoyl CoA) is a substrate of benzoyl-CoA reductase (box A) and a starter substrate for type-III polyketide synthase. It also acts as a substrate for plant enzymes biphenyl synthase (BIS) and benzophenone synthase (BPS). Benzoyl CoA is an effector of gentisate pathway of the bacteria, Comamonas testosteroni. It may also be used as a substrate for the characterization of specific alcohol acyltransferases and N-acyltransferase assays.