Merck, C111030-12X2G, DMT-dC(bz) Phosphoramidite

Name: DMT-dC(bz) Phosphoramidite
Brand: Merck
SKU: C111030-12X2G

Size:12 x 2 g, Cytidine, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], DMT-dC(bz) amidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N, N-?bis(1-methylethyl)phosphoramidite], N4-Benzoyl-5′-O-(4, 4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N, N′-diisopropylphosphoramidite], configured for ABI

Available Catalog Numbers

C111030-12X1G C111030-12X2G

Catalog Number: C111030-12X2G

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Category

Nucleotides & Nucleosides

Pack Size12 x 2 g

TagsChemistry & Biochemicals Biochemicals Nucleosides & Nucleotides

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Proligo′s DNA phosphoramidites lead to high-yield and high-quality oligonucleotides due to their high coupling efficiency. The deprotection step of automated oligonucleotide synthesis is integral to synthesis time and final product quality. Exocyclic amine functions are protected by a benzoyl group (dA(bz) and dC(bz)) or isobutyryl group (dG(ib))Key features of DNA phosphoramidites:Recommended cleavage and deprotection conditions are 8 hours at 55 °Cor 24 hours at room temperature using concentrated ammonia solution, for standard base-protected oligonucleotides
The high coupling efficiency of Proligo′s DNA phosphoramidites leads to high-yield and high-quality oligonucleotides
The product belongs to ABI™ synthesizers.
Legal Information
ABI is a trademark of Applera Corporation or its subsidiaries in the US and/or certain other countries

Specifications

General

NACRES	NA.51
PubChem Substance ID	329774848
UNSPSC Code	41116107
MDL number	MFCD00036315
InChI	1S/C46H52N5O8P/c1-32(2)51(33(3)4)60(57-29-13-27-47)59-40-30-43(50-28-26-42(49-45(50)53)48-44(52)34-14-9-7-10-15-34)58-41(40)31-56-46(35-16-11-8-12-17-35,36-18-22-38(54-5)23-19-36)37-20-24-39(55-6)25-21-37/h7-12,14-26,28,32-33,40-41,43H,13,29-31H2,1-6H3,(H,48,49,52,53)/t40-,41+,43+,60?/m0/s1
SMILES string	COc1ccc(cc1)C(OC[C@H]2O[C@H](C[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)N3C=CC(NC(=O)c4ccccc4)=NC3=O)(c5ccccc5)c6ccc(OC)cc6
InChI key	PGTNFMKLGRFZDX-SALLYJDFSA-N
biological source	non-animal source (no BSE/TSE risk)
type	for DNA synthesis
product line	Proligo Reagents
assay	≥99% (31P-NMR)
form	powder or granules
technique(s)	oligo synthesis: suitable
impurities	≤0.3 wt. % water content (Karl Fischer)
color	white to off-white
<i>λ</i>	conforms (UV/VIS Identity)
compatibility	configured for ABI

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Merck, C111030-12X2G, DMT-dC(bz) Phosphoramidite

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