Merck, C3777-25MG, Casein fluorescein isothiocyanate from bovine milk

General description
Casein is a major milk phospho-protein and constitutes about 80% of the total protein content in milk. Bovine milk is composed of four types of casein such as, αS1, αS2, β, and κ. Casein exists as micelles in milk.
Application
highly sensitive protease substrate
Casein fluorescein isothiocyanate from bovine milk has been used:
as a substrate for semi-quantitative analysis of protease in Arabidopsis cells
to determine the caseinolytic activity of secreted LasB (elastase), alkaline protease and protease IV
for determining the SpeB (cysteine protease) proteolytic activity in Streptococcus pyogenes cells

Biochem/physiol Actions
Casein micelle system is involved in the prevention of pathological calcification of mammary glands.