Merck, C8395-500MG, Cephradine

Name: Cephradine
Brand: Merck
SKU: C8395-500MG

Size:500 mg, Cefradin, ≥90.0% (Cephradine, HPLC)

Catalog Number: C8395-500MG

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Category

Antibiotics & Antimycotics

Pack Size500 mg

TagsChemistry & Biochemicals Biochemicals Antibiotics

CollectionsMerck Biochemicals Collection: Trusted Lab Reagents & Buffers Merck Cell Culture Supplements & Reagents: Complete Solutions for Research & Bioproduction Merck Roche Life Science Products for PCR, RT‑PCR & Nucleic Acid Purification

Description

General description
Chemical structure: β-lactam
Application
Cefradin was used to study the effect of expression, binding, and inhibition of PBP3 and other penicillin-binding proteins (PBPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cefradin is a semi-synthetic cephalosporin that inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins (PBPs), such as PBP3, which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. It is effective against Gram-positive and Gram-negative bacteria. Cefradin may also interfere with autolysin inhibitors.
Other Notes
Keep container tightly closed in a dry and well-ventilated place.

Specifications

General

NACRES	NA.85
PubChem Substance ID	24278342
UNSPSC Code	51282517
MDL number	MFCD00865048
InChI	1S/C16H19N3O4S/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9/h2-3,6,10-11,15H,4-5,7,17H2,1H3,(H,18,20)(H,22,23)/t10-,11-,15-/m1/s1
SMILES string	[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CCC=CC3)C(O)=O
InChI key	RDLPVSKMFDYCOR-UEKVPHQBSA-N
assay	≥90.0% (Cephradine, HPLC)
form	powder
solubility	ethanol: practically insoluble 96%
antibiotic activity spectrum	Gram-negative bacteria
mode of action	cell wall synthesis \| interferes
storage temp.	2-8°C
Quality Level	200

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Merck, C8395-500MG, Cephradine

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